| 1. | | The architecture behind a one-person tech startup (anthonynsimon.com) |
| 1330 points by ksahin on April 8, 2021 | 320 comments |
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| 2. | | The Real Book (99percentinvisible.org) |
| 575 points by mpweiher on April 8, 2021 | 140 comments |
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| 3. | | Home-Built Scanning Tunneling Microscope (2015) (dberard.com) |
| 361 points by _Microft on April 8, 2021 | 79 comments |
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| 4. | | FDA approves first test of CRISPR for genetic defect causing sickle cell disease (news.berkeley.edu) |
| 440 points by zuhayeer on April 7, 2021 | 132 comments |
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| 5. | | An interview with the man who keeps uploading my feet to WikiFeet (thecut.com) |
| 565 points by Jugurtha on April 8, 2021 | 279 comments |
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| 6. | | Surprisingly Slow (gregoryszorc.com) |
| 559 points by dochtman on April 6, 2021 | 148 comments |
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| 7. | | [dupe] Facebook does not plan to notify half-billion users affected by data leak (reuters.com) |
| 667 points by wdb on April 8, 2021 | 298 comments |
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| 8. | | A man is looking for the friends who shipped him overseas in a crate in 1965 (cbc.ca) |
| 400 points by colinprince on April 8, 2021 | 238 comments |
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| 9. | | Why do long options start with two dashes? (2019) (djmnet.org) |
| 356 points by spyh on April 8, 2021 | 246 comments |
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| 10. | | New Mexico is the second state to ban qualified immunity (innocenceproject.org) |
| 418 points by williamsharris on April 8, 2021 | 313 comments |
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| 11. | | A simple C implementation to stream H.264 to browser using WebRTC (github.com/sepfy) |
| 296 points by sepfy on April 8, 2021 | 124 comments |
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| 12. | | AMD and Xilinx Stockholders Overwhelmingly Approve AMD’s Acquisition of Xilinx (amd.com) |
| 275 points by zdw on April 8, 2021 | 93 comments |
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| 13. | | How to make a Python package in 2021 (antonz.org) |
| 396 points by gilad on April 8, 2021 | 205 comments |
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| 14. | | Ory Keto, open source authorization server based on Google Zanzibar (github.com/ory) |
| 251 points by An0mammall on April 8, 2021 | 65 comments |
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| 15. | | Ask HN: Why is the Linux community struggling to implement hibernation? |
| 322 points by cyka178 on April 8, 2021 | 332 comments |
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| 16. | | Why keyboard shortcuts don't work on non-US layouts and how devs could fix it (tkainrad.dev) |
| 253 points by tkainrad on April 8, 2021 | 206 comments |
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| 17. | | Adding is favoured over subtracting in problem solving (nature.com) |
| 196 points by mpweiher on April 7, 2021 | 145 comments |
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| 18. | | Wuffs the Language (github.com/google) |
| 187 points by bshanks on April 7, 2021 | 75 comments |
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| 19. | | GNU lightning: generates assembly language code at run-time (gnu.org) |
| 161 points by mpsq on April 7, 2021 | 75 comments |
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| 20. | | Muon G-2 Experiment at Fermilab Finds Hint of New Particles (quantamagazine.org) |
| 135 points by gmays on April 8, 2021 | 61 comments |
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| 21. | | Show HN: A Twitter crawler for app ideas (iwishtherewas.app) |
| 272 points by mulhoon on April 8, 2021 | 124 comments |
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| 22. | | Netscape ISP Homepage (netscape.com) |
| 165 points by fireeyed on April 8, 2021 | 117 comments |
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| 23. | | Run Bhyve in FreeBSD jails – The view from inside the forest (2020) (byteswizards.com) |
| 98 points by rodrigo975 on April 8, 2021 | 14 comments |
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| 24. | | GnuCOBOL – a free/libre COBOL compiler (gnucobol.sourceforge.io) |
| 122 points by pabs3 on April 8, 2021 | 55 comments |
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| 25. | | Proofs, Computability, Undecidability, Complexity, and the Lambda Calculus [pdf] (upenn.edu) |
| 135 points by bmc7505 on April 8, 2021 | 72 comments |
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| 26. | | Commits are snapshots not diffs (2020) (github.blog) |
| 323 points by warpech on April 8, 2021 | 307 comments |
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| 27. | | A skeptic’s take on Neuralink and other consumer neurotech (statnews.com) |
| 109 points by hhs on April 8, 2021 | 158 comments |
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| 28. | | lscpu + neofetch = cpufetch (github.com/dr-noob) |
| 130 points by luke2m on April 8, 2021 | 32 comments |
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| 29. | | The NoPhone (thenophone.com) |
| 253 points by bdeshi on April 7, 2021 | 145 comments |
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| 30. | | The history of UTF-8 as told by Rob Pike (2003) (cat-v.org) |
| 244 points by quyleanh on April 8, 2021 | 116 comments |
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| More |